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 Biography   Jay M. Baraban, M.D., Ph.D. Professor Departments of Neuroscience, and of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine To Dr. Baraban, one of the most fascinating questions facing neuroscience is how the nervous system learns. Recent studies indicate that this process involves changes in neuronal morphology, the form and structure of nerve cells, and synaptic efficacy in the communication between cells, or neuronal plasticity. Defects in these processes underlie mental retardation and other neuropsychiatric diseases. Dr. Baraban and his team are studying the intracellular signaling pathways that mediate neuronal plasticity. Among the subjects under investigation are: a protein that triggers rapid changes in dendritic morphology (dendrites are message-carrying extensions from neurons); a pair of proteins that target messenger RNAs, bearers of the genetic message, to the vicinity of synapses; and a gene that regulates the aversive responses induced by opiate withdrawal. A member of NARSAD’s Scientific Council since 2001, Dr. Baraban received a NARSAD Independent Investigator Award in 1997. |
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