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 Biography   Francine Benes, M.D., Ph.D. Professor of Psychiatry Harvard Medical School Director, Program in Structural and Molecular Neuroscience Harvard Brain Tissue Resource Center McLean Hospital Over the past 25 years, Dr. Benes has devoted her career to the study of the limbic lobe, the part of the brain that helps to regulate emotion and emotional memory, in subjects with schizophrenia and bipolar disorder. She has used a combination of approaches, including microscopic studies of receptor binding activity and biochemical and genetic techniques to study the ways in which the glutamate, GABA and monoaminergic neurotransmission systems are "mis-wired" in the limbic lobe. Most recently, Dr. Benes and her colleagues have been using a combination of laser capture microdissection, gene-expression profiling and network association analysis to identify groups of genes that might be associated with the respective endophenotypes (genetic variants) for schizophrenia and bipolar disorder. Dr. Benes joined NARSAD’s Scientific Council in 2001 and received the NARSAD Lieber Prize for Outstanding Achievement in Schizophrenia Research in 2002. |
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