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![]() Ronald S. Duman, Ph.D. Professor of Psychiatry and Pharmacology Director, Division of Molecular Psychiatry and Abraham Ribicoff Research Facilities Yale University Dr. Duman’s laboratory focuses on identifying the molecular and cellular adaptations that underlie the brain’s response to stress and to psychotropic drugs. These include adaptations of cell receptors, signal transduction proteins, gene transcription factors, and neurotrophic factors, such as growth factors, that act on nerve cells. While various adaptations in response to stress contribute to mood disorders, including depression, they also, conversely, contribute to the beneficial actions of psychotropic drugs. Dr. Duman’s research has shown that antidepressants increase cell growth, which he believes may explain in part how these drugs produce their therapeutic effects. His NARSAD honors include a Young Investigator Award in 1989, an Independent Investigator Award in 1997, a Distinguished Investigator Award in 2005, and the Falcone Prize for Outstanding Achievement in Affective Disorders Research in 2002. Dr. Duman has been a NARSAD Scientific Council member since 2004. |
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