Meet the Scientist - December 2016

About This Webinar:

In this month's webinar, Dr. Yvette I. Sheline will explain neuroinflammatory hypotheses of depression and PTSD treatment.

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Presented by:

Yvette I. Sheline, M.D.

Yvette I. Sheline, M.D.

Foundation Scientific Council Member
NARSAD Grantee, 1998, 2002, 2005
Professor of Psychiatry, Radiology, Neurology
Director, Center for Neuromodulation in Depression and Stress (CNDS)
University of Pennsylvania Perelman School of Medicine

Dr. Yvette Sheline is known for her pioneering studies of hippocampal volume loss in major depression and the moderating effects of antidepressant treatment, work widely cited in psychiatric literature. Her research has also integrated structural/functional neuroimaging with depression course, neuropsychological correlates, and treatment outcomes. She seeks to determine how depression affects the brain using neuroimaging techniques, and to understand how stress produces functional dysregulation. Dr. Sheline investigates treatment effects of antidepressants and cognitive behavioral therapy on emotion-induced fMRI activity in PTSD and depression; longitudinal effects of treatment on neuropsychological and brain structural variables in late-life depression; and modifiers of brain amyloid binding in normal aging and preclinical Alzheimer’s Disease.

Prior to joining the faculty at Penn, Dr. Sheline was Professor of Psychiatry and Director, Center for Depression Stress and Neuroimaging at Washington University School of Medicine in St. Louis.


Jeffrey Borenstein, M.D.

Jeffrey Borenstein, M.D.

President & CEO, Brain & Behavior Research Foundation

Jeffrey Borenstein, M.D., joined the Brain & Behavior Research Foundation in 2012 as Chief Medical Officer and was appointed as President & Chief Executive Officer at the start of 2013. Dr. Borenstein has more than two decades of experience in health and non-profit leadership. He is former CEO/Medical Director of Holliswood Hospital, where he served from 1996 to 2012. He is a board-certified psychiatrist and the Host of the award-winning series, “Healthy Minds,” which is broadcast on public television stations across the United States. He is Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association.

An active contributor to the psychiatric field  for more than three decades, Dr. Borenstein currently chairs the Council on Communications of the American Psychiatric Association, the Mental Health Services Council of NY State, and the Section on Psychiatry, NY Academy of Medicine, where he is a Fellow. Among the many honors to his credit are the National Alliance on Mental Illness of NY State Connie Lieber Award, the American Psychiatric Association Special Presidential Commendation and the Federation of Organizations Community Mental Health Man of the Year Award.

Dr. Borenstein is Associate Clinical Professor of Psychiatry, Columbia University College of Physicians & Surgeons. He is a graduate of Harvard College and New York University School of Medicine.

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