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 News & Events  A study published in the June 17 issue of JAMA, the Journal of the American Medical Association, contradicts the findings of a much-celebrated 2003 report, which stated that genetic variation of the serotonin transporter gene, interacting with stressful life events, plays a role in predisposition to major depression. [more] Herbert Pardes Building Dedicated at NYS Psychiatric Institute Leaders from government and mental health care celebrated the dedication of the Herbert Pardes Building of the New York State Psychiatric Institute at a special ceremony on May 15, 2009. The building honors NARSAD Scientific Council President Herbert Pardes, M.D., a giant in American healthcare and psychiatric research, who is president and CEO of New York-Presbyterian Hospital and Healthcare System and formerly headed the institute and served as director of the National Institute of Mental Health. [more] NARSAD Investigator Aids in Capturing the Birth of a Synapse A research team that includes NARSAD Independent Investigator A. Kimberley McAllister, Ph.D., has identified the locking mechanism that allows some neurons to form synapses. Mutations of genes that produce a critical cell-adhesion molecule involved in the research have been linked to autism. The discovery, captured with fluorescent imaging of neurons harvested from rat pups shortly after birth and studied in culture as they developed, was reported online in the journal Neural Development. [more] NARSAD Researcher Discovers Similar Cell Dysfunction in Sanfilippo Syndrome and Alzheimer’s Researchers seeking to understand the causes of Sanfilippo syndrome type B, a rare genetic lysosomal storage disease, were surprised to find protein aggregates known as neurofibrillary tangles that are usually seen in Alzheimer’s and other forms of dementia. The syndrome causes profound mental retardation, behavior problems and, frequently, death before the age of 20. The researchers are hopeful that these patients may one day benefit from new Alzheimer’s treatments. [more] Study Helps Confirm Role of Kynurenic Acid in Schizophrenia and Why Smoking Relieves Symptoms Levels of kynurenic acid are elevated in the brain and cerebrospinal fluid of people with schizophrenia and Alzheimer’s disease, and the substance has been suspected of a role in the cognitive dysfunction characteristic of both these disorders. Now, studies by NARSAD 2007 Young Investigator David Bucci, Ph.D., of Dartmouth College, have shown that elevated concentrations of endogenous kynurenic acid interfere with contextual learning and memory. [more] Citalopram Ineffective as Drug for Autism, Causing Significant Side Effects NARSAD Investigator Linmarie Sikich, M.D., of the University of North Carolina at Chapel Hill School of Medicine, co-authored a study, the largest to date of children with autism, which found that a drug commonly given to children with autism to reduce repetitive behaviors is ineffective compared to placebo, and in some children may actually increase repetitive behaviors. [more] Post Traumatic Stress Disorder and Depression in Mothers Post 9/11 Linked to Increased Behavioral Problems in Children Preschool children whose mothers had posttraumatic stress disorder (PTSD) and depression, as a result of exposure to the World Trade Center (WTC) attacks, were more likely to have behavioral problems. This new research from Mount Sinai School of Medicine appears in the journal Archives of Pediatrics and Adolescent Medicine. [more] Care Costs for Bipolar Disorder Higher Than for Diabetes and Other Chronic Diseases A study reviewing health-care claims over a four-year period showed that patients with bipolar disorder had significantly higher monthly costs compared with patients with other chronic conditions, such as diabetes, depression, asthma or coronary artery disease. Only patients with both coronary artery disease and diabetes had higher costs than patients with bipolar disorder. [more] » More Research & Giving News
Genetic Variant Implicated in Schizophrenia and Bipolar Disorder Appears to Impair Communication in the Brain May 26, 2009 Using Light to Alter Neural Activity May 26, 2009 For Proper Brain Function, Cells Need to Keep the Beat May 26, 2009 Disrupting Brain Protein Produces Antidepressant Effect in Mice May 26, 2009 News Archive |
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