Project Summary

Amanda R. Bolbecker, Ph.D. (Young Investigator 2007) of Indiana University, plans to investigate the neural timing circuits in bipolar disorder (BD) using eyeblink-conditioning (EBC) methodology. While there is evidence of structural abnormalities in BD, very little is known about whether functional deficits, such as neural timing, exist. EBC methodology is well-suited for testing the functional integrity of cerebellar timing circuitry and provides a mechanism for testing the hypothesis that neural timing deficits may contribute to characteristic symptoms of BD.

Program Area: MOOD DISORDERS\Bipolar\Bipolar I

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