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 Project Summary  Xiang Cai, Ph.D. (Young Investigator 2007) of the University of Maryland, will test several hypotheses relating to serotonin actions, particularly serotonin 5-HT1B receptors, on glutamate transmission since it is poorly understood and dysfunction of serotonergic regulation is implicated in a variety of psychiatric disorders including depression and schizophrenia. Dr. Cai’s experiments are proposed with the belief that a clearer understanding of the roles of serotonin 5-HT1BRs in regulating glutamatergic synaptic transmission may provide insights to more effective future therapies for disabling affective and behavioral disorders. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizoaffective Disorder\Depressive Type |
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Mei Huang, Ph.D., Vanderbilt University Medical Center, 2005 & 2007 Young Investigator