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 Project Summary  Ted M. Dawson, M.D., Ph.D. (Independent Investigator 2000) of Johns Hopkins University, is investigating the role of a chemical called nitric oxide synthase (nNOS) in brain development and function. This enzyme is involved in brain formation and neurochemistry, and in the regulation of behavior. Animals without nNOS have a loss of social inhibition and in the ability to recognize social cues. nNOS is also involved in the release of dopamine and glutamate, two neurotransmitter systems that are implicated in the biochemical pathology of schizophrenia. Nitric oxide also appears to be essential for the survival of functioning neurons. Dr. Dawson aims to identify the critical elements involved in these effects of nNOS, including the genes that are involved in its various functions. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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NARSAD Award Winners
 Colleen Ann McClung, Ph.D., UT Southwestern Medical Center at Dallas, 2005 & 2007 Young Investigator Latest News from NARSAD
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