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Christina L. Fales, Ph.D. (Young Investigator 2007) of Washington University School of Medicine, seeks to understand the brains basis for negative attentional bias in generalized anxiety disorder (GAD). Dr. Fales hypothesizes that anxiety inclines people to a reactive style of cognitive control that makes inefficient use of working memory areas (dorsolateral prefrontal cortex) and allows over-activation of emotion-related areas that are normally regulated by prefrontal cortex. This over-activation may play a causal role in the inability of GAD sufferers to turn off perseverative negativity. Program Area: MULTIPLE FOCUS\Anxiety Disorders/Mood Disorders |
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