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 Project Summary  Susan E. Holmes, Ph.D. (Young Investigator 2001) of Johns Hopkins University, is conducting a systematic search for expansion mutations in schizophrenia. This type of mutation involves trinucleotide repeats, three of the bases of DNA which are consecutively repeated within a DNA region. It is believed that patients with schizophrenia have more of these repeats. Dr. Holmes will identify these mutations in two subjects with schizophrenia, and then screen a large set of patients with schizophrenia for these repeat-containing genes. This work may lead to characterization of a class of genes that may play an important causal role in schizophrenia. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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 Colleen Ann McClung, Ph.D., UT Southwestern Medical Center at Dallas, 2005 & 2007 Young Investigator Latest News from NARSAD
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