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 Project Summary  Samie R. Jaffrey, M.D., Ph.D. (Young Investigator 2000) of Weill Medical College of Cornell University, is investigating the mechanisms by which nitric oxide affects brain function. Nitric oxide is proposed to mediate the effects of the NMDA receptor, abnormalities of which have been implicated in schizophrenia. Dr. Jaffrey will use an assay to detect proteins that have been modified by nitric oxide to form S-nitrosylated derivatives. By characterizing this signaling pathway, and identifying these proteins, the molecular actions of NMDA receptor function will be clarified. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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 Colleen Ann McClung, Ph.D., UT Southwestern Medical Center at Dallas, 2005 & 2007 Young Investigator Latest News from NARSAD
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