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 Project Summary  Yong Ke, Ph.D. (Young Investigator 2004) of McLean Hospital/Harvard University, aims to use a novel magnetic resonance spectroscopy method to improve measurements of N-acetyl aspartate (NAA), a neuronal cell marker in schizophrenia. In the proposed project, Dr. Ke will use what is called the J-resolved ID MRS technique, which increases the accuracy of the NAA measurement by reducing the amount of overlapping peaks of NAA that occur with conventional proton ID spectra. The new method also reduces the time it takes to perform other measurements compared with current techniques. As a result, this new MRS method will allow Dr. Ke to perform a detailed study on frontal lobe NAA. Better understanding of NAA abnormality in schizophrenia should be gained from this investigation. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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 Colleen Ann McClung, Ph.D., UT Southwestern Medical Center at Dallas, 2005 & 2007 Young Investigator Latest News from NARSAD
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