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 Project Summary  Michael Krause, Ph.D. (Young Investigator 2007) of Baylor College of Medicine, plans to create a rodent model of schizophrenia to study neural activity in the striatum, a brain region that shows a loss of certain neurons in schizophrenia patients. The study will entail advanced methods of neural surgery, intrabrain injections and specialized recording techniques. Dr. Krause hopes his group’s findings will lead to better understanding of striatal circuit activity and better treatment for schizophrenia. It may provide also broader insights since striatal dysfunction may be involved Alzheimer’s and Parkinson’s disease and other brain disorders. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia\Basal Ganglia Diseases |
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Mei Huang, Ph.D., Vanderbilt University Medical Center, 2005 & 2007 Young Investigator