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Wesley K. Kroeze, Ph.D. (Young Investigator 2001) of Case Western Reserve University, is characterizing genes that are regulated by drugs and medications that bind to the serotonin type 2A (5HT-2A) receptor. When brain cells are exposed to these drugs, they activate certain genes to produce proteins by a coordinated series of events known as transcription and translation. A powerful molecular biological technique will be used to demonstrate which genes are up- and down-regulated by these drugs. The knowledge to be gained from this study may help to better understand how antipsychotic and antidepressant medications function. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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