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 Project Summary  Fabio Macciardi, M.D., Ph.D. (Independent Investigator 2000) of Centre For Addiction and Mental Health, will apply a sophisticated molecular genetic called haplotype linkage disequilibrium analysis, in an attempt to isolate a gene that increases risk for schizophrenia. Previous work suggests that such a gene may reside on chromosome 22. The haplotype linkage disequilibrium test permits the evaluation of the joint effect of multiple genes, or of multiple variants within one gene. Dr. Macciardi will study a large sample of schizophrenic patients and their families in order to characterize the presence of one or more susceptibility genes in the region of chromo-some 22 that has been associated with an increased risk of schizophrenia. The identification of such genes holds promise toward preventing and better understanding the pathogenesis of schizophrenia. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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 Colleen Ann McClung, Ph.D., UT Southwestern Medical Center at Dallas, 2005 & 2007 Young Investigator Latest News from NARSAD
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