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Laszlo A. Papp, M.D. (Independent Investigator 2000) of Columbia University, will examine the effectiveness of cognitive behavioral therapy (CBT) in elderly patients who have both depression and anxiety disorders. Previous studies routinely exclude elderly patients with these conditions from pharmacologic trials and, in addition, elderly patients generally suffer more side effects to antidepressants. Dr. Papp will therefore administer CBT to 20 elderly patients with both depression and anxiety, in addition to CBT “booster” sessions. Non-responders will receive venlafaxine (Effexor) followed by a trial of mirtazepine (Remeron). The results from this study will be used to refine a CBT manual developed from this work, optimize pharmacotherapy for non-responders, and design a controlled study with a larger sample size. Program Area: MULTIPLE FOCUS AREAS\Mood Disorders/Anxiety Disorders |
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