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 Project Summary  Martin P. Paulus, Ph.D. (Young Investigator 2000) of University of California, San Diego, is testing the hypothesis that the interaction between different cortical brain regions in schizophrenia is dynamically dysregulated. Such dysregulation could involve either too strong or too weak connectivity, leading to behavioral sequences that are abnormally connected over time. To address this question, patients with schizophrenia will be compared with controls performing a two-choice guessing task during a functional magnetic resonance imaging (fMRI) scan. The results of this experiment could significantly increase our understanding of how neural systems dysfunction relates to thought disorder and disorganized behavior in schizophrenic patients. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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 Colleen Ann McClung, Ph.D., UT Southwestern Medical Center at Dallas, 2005 & 2007 Young Investigator Latest News from NARSAD
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