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Maria del Mar Sanchez, Ph.D. (Young Investigator 2002) of Emory University, will analyze cellular and molecular alterations in neural systems in juvenile rhesus monkeys that have experienced separation from their mothers and social group. From this model, Dr. Sanchez hopes to investigate how early adverse experience affects the development of neurocircuits regulating the hypothalamus-pituitary-adrenal (HPA) and hypothalamus-pituitary-thyroid (HPT) axes as well as systems mediating fear and anxiety. Increasing evidence indicates that the experience of early adversity may interact with the genetic background to increase n individual's vulnerability to the development of anxiety and affective disorders: therefore, Dr. Sanchez will study mechanisms which may contribute to the risk for development of mood disorders. Program Area: MULTIPLE FOCUS AREAS\Mood Disorders/Anxiety Disorders\Child/Adolescent |
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