Project Summary

Moriah E. Thomason, Ph.D. (Young Investigator 2008) of Stanford University, plans to explore aspects of brain function that are associated with genetic polymorphisms in the promoter region (5-HTTLPR) of the 5-HTT gene in children, as well as to examine whether cortisol response to stress is associated either with genotype or with measures of brain function. This project will further our understanding of genetic vulnerability to disorder, of mechanisms by which genes predict adverse outcomes, and of the developmental emergence of increased neural response in frontal and limbic regions that are critical for the processing of negative emotion.

Program Area: MULTIPLE FOCUS\Anxiety Disorders/Mood Disorders

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