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Project Summary

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Jeffrey A. Welge, Ph.D. (Young Investigator 2005) of the University of Cincinnati, plans to study the effectiveness of psychological assessment scales to measure changes in symptoms of major mental disorders. In the proposed study Dr. Welge will use databases of patients with schizophrenia (N=768) and bipolar mania (N=500-800) who participated in recent clinical trials to measure detection thresholds for three widely used symptom severity scales (YMRS, BPRS, and PANSS). Psychometric assessment of changes on individual items will be performed to assess the validity of conventional scoring rules and to suggest refinements. Psychometric analyses will also be used to determine whether perceived change in symptoms that occur in both mania and schizophrenia (e.g., symptoms of psychosis) contributes differently to perceived global change in these conditions.

Program Area: MULTIPLE FOCUS AREAS\Bipolar Disorder/Schizophrenia

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Announcements
2008/2009 NARSAD Grant Deadlines:

2008 Independent Investigator application deadline: March 5, 2008

2008 Young Investigator, 2008 Distinguished Investigator and 2008 Staglin Grantees Announced: March, 2008

2008 Distinguished Investigator Earliest Start Date: May 1, 2008

2009 Distinguished Investigator Award application deadline: May 15, 2008

2008 Young Investigator Earliest Start Date: July 1, 2008

2009 Young Investigator Award application deadline: July 25, 2008

2008 Independent Investigator Award Earliest Start Date: September 15, 2008

2008 Staglin Award Earliest Start Date: September 15, 2008

2009 Distinguished Investigator Earliest Start Date: May 1, 2009

2009 Young Investigator Earliest Start Date: July 1, 2009





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