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Eric Zarahn, Ph.D. (Young Investigator 2002) of Columbia University, will use an event-related functional magnetic resonance imaging method to obtain separate measurements of neural activity during encoding, information maintenance, and motor response components of a working memory (WM) task in control subjects and subjects with schizophrenia. Dr. Zarahn is attempting to understand the neural mechanisms underlying the WM deficits present in schizophrenia. Cortical inefficiency is believed to be related to the cognitive dysfunction experienced in schizophrenia. This project will investigate the hypothesis of cortical inefficiency as a neural mechanism of WM deficits in schizophrenia. Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS\Schizophrenia |
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