SSRI

Combining Antidepressants Can Improve Outcomes in Patients with Severe Depression, Study Finds
A study analyzing the results of 39 previous clinical trials involving 6,751 depressed patients concludes that it can be more effective to treat with two antidepressant drugs rather than a single… Read More
Early Reductions in Irritability Are Found to Predict Treatment Results in Some Patients with Major Depression
Results of a clinical trial indicate that patients with major depression who become less irritable within 4 weeks of initiating treatment with an antidepressant medicine are much more likely to have… Read More
Abstract shape of bone structure
One of the side effects of using antidepressant medications of the SSRI class (selective serotonin reuptake inhibitors) may be an increased risk of bone loss and fractures. A study published… Read More
Newly Discovered Brain Circuit
Serotonin, a neurotransmitter whose levels are boosted by certain antidepressant medications, is best known for its role in regulating mood in a positive way. But the same neurotransmitter can also… Read More
How Ketamine Exerts its Rapid Antidepressant Effects
Foundation-supported scientists have just solved an important mystery. They have determined how ketamine, a drug approved long ago as an anesthetic but used recently on an experimental basis in… Read More